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Lab-Quality Thrombosis Testing with Poclight D-Dimer POC CLIA

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Lab-Quality Thrombosis Testing with Poclight D-Dimer POC CLIA

Lab-Quality Thrombosis Testing with Poclight D-Dimer POC CLIA
October 13, 2025
1.  Thrombosis: An Overlooked Threat
 

The International Society on Thrombosis and Haemostasis (ISTH) established World Thrombosis Day (WTD) on October 13 to raise awareness of the global health threat.

Every year, 1 in 4 people worldwide die from conditions related to thrombosis, the underlying cause of the top three cardiovascular killers: heart attack, stroke, and venous thromboembolism (VTE). - World Thrombosis Day website (2025)

Venous Thromboembolism (VTE)

 

According to WHO data (2001–2023), the global age-standardized mortality rate of pulmonary embolism fell from 3.49 to 2.42 per 100,000. However, rates are rising in some lower-middle-income regions, underscoring the need to strengthen diagnostic capacity. Rapid and accessible POC testing helps bridge this gap where laboratory resources are limited.

 

2.  D-Dimer Testing Essentials

 

D-dimer is a specific fibrinolysis marker and key laboratory indicator of thrombus formation and breakdown. It rises within 2 hours of clot formation, has a 7-8 hour half-life, and remains stable in blood samples for 24-48 hours. These characteristics ensure its crucial role in diagnosing and monitoring thrombotic diseases.

Its clinical applications may include the following:

● Early Detection of Thrombosis: D-dimer testing is widely used to help rule out venous thromboembolism (VTE) in patients with suspected thrombotic events, particularly when combined with clinical assessment. Rapid detection supports prompt management decisions.

● Guiding Further Assessment: Prompts additional imaging or diagnostic tests.

● Supporting Anticoagulation Decisions: Helps guide initiation, adjustment, or duration of anticoagulant therapy.

Test Combination

Item

Clinical Use / Recommendation

D-dimer Test Kit

Helps rule out suspected DVT or PE (when combined with clinical probability assessment)

D-dimer + NT-proBNP Test Kit

Assists in differentiating PE from heart failure in patients with acute dyspnea

D-dimer + NT-proBNP and/or Troponin I

Helps rule out PE and assess PE prognosis

Note: D-Dimer levels can rise due to infection, inflammation, surgery, or pregnancy. It should always be interpreted alongside clinical findings and imaging.

 

3.  Poclight D-Dimer Solutions

 

D-Dimer Test Kit

Highly cost-effective, Poclight Biotech’s point-of-care D-dimer Test Kit solutions deliver results within 5 minutes, supporting prompt assessment and care.

Our Stand-out features:

1)  Small Sample Volume & Rapid Results

Only 50 μL of serum or plasma needed, with 5-minute turnaround, ideal for fast clinical decisions.

Parameter

Sample type

Assay duration

Sample volume

Cut-Off value

Measuring range

D-dimer

Plasma

5min

50 μL

0.5 mg/L, Higher D-dimer levels suggest clotting activity

0.25~20 mg/L

 

2)  Freeze-dried reagents: no cold chain, 18 months shelf life, simplifying storage and transport.

3)  High accuracy and excellent precision (CV < 5%)

 

DDimer Performance

 

4)  Applicable with the C5000 POC CLIA Analyzer: 3-Step Operation, Maintenance-Free

C5000 Operation

 

Contact us to learn about local distributors and pricing options for Poclight D-dimer solutions.

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